✓ Gynécologie de l'enfant et de l'adolescente - N°31 ↠ Kindle Auteur ✓ Elisabeth Thibaud Évaluations des utilisateurs

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Biosynthse et mcanisme d action des strodes sexuels Points essentiels Les strodes jouent un rle majeur en endocrinologie et reproduction, mais aussi dans de nombreux processus physiologiques incluant la diffrenciation cellulaire et le dveloppement Ils agissent en se fixant des rcepteurs qui activent la transcription par l intermdiaire des corgulateurs Une altration des voies de signalisation qui leur sont associes conduit de nombreuses maladies humaines Les rcepteurs et leurs corgulateurs sont des cibles thrapeutiques d intrt majeur pour la prise en charge de pathologies hormonodpendantes, cancreuses notamment, mais aussi des infertilits, de la mnopause Ce chapitre rappelle brivement les donnes rcentes sur la biosynthse des hormones strodes, ainsi que les principales tapes molculaires du mcanisme gnomique de leur action, leur implication en physiopathologie humaine et les applications thrapeutiques potentielles Les hormones strodes sont des drivs du cholestrol Elles comportent cinq grandes classes d une part oestrognes, progestrone et andrognes strodes sexuels , produits par les gonades, d autre part glucocorticodes et minralocorticodes strodes surrnaliens , produits par la corticosurrnale Elles agissent en se fixant un rcepteur intracellulaire spcifique appartenant la superfamille des rcepteurs nuclaires Ces rcepteurs sont des facteurs de transcription activs par leur ligand Ils forment une vaste famille de molcules responsables de la rgulation de l expression de gnes cibles Le squenage du gnome humain a montr que cette superfamille de protines comporte plus de 49 membres chez l homme, dont la classification et la nomenclature ont t acceptes en 1999 1.1 Ces rcepteurs nuclaires sont schmatiquement regroups en quatre types en fonction de la nature de leur ligand et de leur interaction avec l ADN le type I associe les rcepteurs des hormones strodes rcepteurs des oestrognes ER , de la progestrone PR , de l aldostrone, des andrognes AR , des glucocorticodes GR et des minralocorticodes MR le type II regroupe les rcepteurs des hormones thyrodiennes, de l acide rtinoque, de la vitamine D et des rcepteurs de divers lipides le type III est compos de rcepteurs dits orphelins, dont le facteur COUP le type IV est reprsent par les rcepteurs orphelins monomriques de type SF1 ou NURR1 Les membres de cette superfamille de rcepteurs nuclaires sont de structure trs proche, et leur mcanisme d action est hautement conserv Par modlisation molculaire, il a t montr qu ils drivent d un anctre commun 1.2 Ils exercent de multiples fonctions dans le dveloppement, la diffrenciation, le mtabolisme et la reproduction, notamment Une anomalie de ces rcepteurs peut conduire de multiples pathologies chez l homme Prendre en charge les problmes poss par les anomalies et les maladies des organes gnitaux et de leur fonction, depuis la priode antnatale jusqu la fin de l adolescence, est le champ d expertise de la gyncologie pdiatrique. Sa spcificit s est impose avec une dfinition plus prcise des abords cliniques et instrumentaux adapts cet ge, le dveloppement des moyens biologiques, d imagerie et gntiques, mais aussi une meilleure analyse et prise en compte du contexte psychologique et social. Cet ouvrage prsente les donnes physiologiques fondamentales permettant la comprhension des pathologies et des choix thrapeutiques Pour aider le praticien dans son exercice, les aspects pratiques de la gyncologie prpubertaire sont dvelopps. L impact des pathologies chroniques, le diagnostic et la prise en charge des anomalies du dveloppement sexuel, les anomalies de la mise en place de la pubert ou de la fonction de reproduction, l abord mdicochirurgical des pathologies tumorales et malformatives, l accompagnement des adolescentes dans l entre dans la vie sexuelle sont traits, en tenant compte des connaissances les plus rcentes, avec l objectif de rpondre aux questions des praticiens. Gyn Wikipedia A gyn is a form of three legged lifting device used on sailing shipsIt provides stability than a derrick or sheers, and requires no rigging for support However, it can only be used for lifting things directly up and down Medical Definition of OB GYN MedicineNet Read medical definition of OB GYN OB GYN A commonly used abbreviation OB is short for obstetrics or for an obstetrician, a physician who delivers babies Obstetrics and gynaecology Wikipedia Obstetrics and gynecology commonly known as OB GYN, OBG, OG or obs and gynae is the medical specialty that deals with pregnancy, childbirth, and the postpartum period and the health of the female reproductive systems vagina, uterus, and ovaries and the Your First Gynecologist Visit Pelvic Exams and STD Tests When to have your first gynecology exam and Pap test, as well as when to see your Ob Gyn for subsequent pelvic exams GYN definition of GYN by Medical dictionary Disclaimer All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only OB GYN VHC Physician Group VHC Physician Group OB GYN provides comprehensive obstetric and gynecologic care services to patients in the Northern Virginia area Learn More Gynecology definition of gynecology by Medical gynecology gi n , jin kolah je the study of diseases unique to women, especially those of the genital tract and breasts gynecology GYN , g n kol Ob gyn Definition of Ob gyn by Merriam Webster Seen and Heard What made you want to look up ob gyn Please tell us where you read or heard it including the quote, if possible Gynecologist OBGYN Brooklyn Manhattan New NYOBGYN of Mount Sinai is a leader in providing high quality, comprehensive health care in Obstetrics and Gynecology to women from OB Gyn Associates PC Cedar Rapids, IA Cedar Rapids, IA OB Gyn Associates PC is Cedar Rapids area s largest Obstetrics Gynecology clinic with on site facilities to care for all your women s health needs GYN Definition by AcronymFinder The World s most comprehensive professionally edited abbreviations and acronyms database All trademarks service marks referenced on this site are properties of their respective owners MCW Department of Obstetrics Gynecology Physicians Our team provides expertise in all aspects of women s health including high risk maternal fetal medicine, reproductive endocrinology and infertility, pediatric and adolescent gynecology, minimally invasive surgery, female urinary incontinence, and oncology Annual Gynecological Exams What to Expect SexInfo Annual Gynecological Exam In order to maintain good reproductive and sexual health, females should visit a gynecologist a doctor who specializes in females reproductive health for an exam about once per year Gynecology UCLA Obstetrics and Gynecology, Los Gynecology Learn about the Gynecology Division at UCLA in Los Angeles, CA Gyn Wikipedia A gyn is a form of three legged lifting device used on sailing shipsIt provides stability than a derrick or sheers, and requires no rigging for support However, it can only be used for lifting things directly up and down Medical Definition of OB GYN MedicineNet Read medical definition of OB GYN OB GYN A commonly used abbreviation OB is short for obstetrics or for an obstetrician, a physician who delivers babies Obstetrics and gynaecology Wikipedia Obstetrics and gynecology commonly known as OB GYN, OBG, OG or obs and gynae is the medical specialty that deals with pregnancy, childbirth, and the postpartum period and the health of the female reproductive systems vagina, uterus, and ovaries and the Your First Gynecologist Visit Pelvic Exams and STD Tests When to have your first gynecology exam and Pap test, as well as when to see your Ob Gyn for subsequent pelvic exams GYN definition of GYN by Medical dictionary Disclaimer All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only OB GYN VHC Physician Group VHC Physician Group OB GYN provides comprehensive obstetric and gynecologic care services to patients in the Northern Virginia area Learn More Gynecology definition of gynecology by Medical gynecology gi n , jin kolah je the study of diseases unique to women, especially those of the genital tract and breasts gynecology GYN , g n kol Ob gyn Definition of Ob gyn by Merriam Webster Seen and Heard What made you want to look up ob gyn Please tell us where you read or heard it including the quote, if possible Gynecologist OBGYN Brooklyn Manhattan New NYOBGYN of Mount Sinai is a leader in providing high quality, comprehensive health care in Obstetrics and Gynecology to women from OB Gyn Associates PC Cedar Rapids, IA Cedar Rapids, IA OB Gyn Associates PC is Cedar Rapids area s largest Obstetrics Gynecology clinic with on site facilities to care for all your women s health needs GYN Definition by AcronymFinder The World s most comprehensive professionally edited abbreviations and acronyms database All trademarks service marks referenced on this site are properties of their respective owners MCW Department of Obstetrics Gynecology Physicians Our team provides expertise in all aspects of women s health including high risk maternal fetal medicine, reproductive endocrinology and infertility, pediatric and adolescent gynecology, minimally invasive surgery, female urinary incontinence, and oncology Annual Gynecological Exams What to Expect SexInfo Annual Gynecological Exam In order to maintain good reproductive and sexual health, females should visit a gynecologist a doctor who specializes in females reproductive health for an exam about once per year Gynecology UCLA Obstetrics and Gynecology, Los Gynecology Learn about the Gynecology Division at UCLA in Los Angeles, CA

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